Police were called at 00:45hrs on Wednesday, 25 December, following reports of a road traffic collision and a car driving on the wrong side of the road on Shaftesbury Avenue, W1.
Four pedestrians have been taken to hospital, with one remaining in a life-threatening condition.
The driver, a 31-year-old man, has been arrested on suspicion of attempted murder.
Deputy Assistant Commissioner Stuart Cundy said, “Officers responded quickly to this report, working closely with City of London Police to arrest a man within minutes.
“Detectives are quickly progressing enquiries as part of this investigation. It’s believed that the suspect was involved in an altercation at a nightclub prior to getting in his car and mounting the pavement.
“Several scenes remain in place at the location today.
“This has been confirmed as an isolated incident which is not terrorism-related.”
